Clozapine-induced neutropenia – or not
نویسندگان
چکیده
منابع مشابه
Clozapine-Induced Febrile Neutropenia and Cellulitis
Clozapine is one of the atypical antipsychotics and is frequently prescribed to patients with treatment-resistant schizophrenia. Agranulocytosis is a major side effect that may lead to death, which limits its use. This is a case report of a patient that developed febrile neutropenia and cellulitis after treatment with clozapine for 20 weeks.
متن کاملRechallenge with clozapine following leucopenia or neutropenia during previous therapy.
BACKGROUND Further treatment with clozapine is contraindicated in any patient who has previously experienced leucopenia or neutropenia during clozapine therapy. AIMS To investigate the results of such a rechallenge in 53 patients. METHOD An analysis was made of the demographic, haematological and outcome data of patients in the UK and Ireland who were rechallenged with clozapine following l...
متن کامل[Hematological alterations associated to olanzapine use after clozapine-induced neutropenia].
O presente re la to é compat íve l com a hipótese de Thangadurai et al. descrita acima, mas sugere que a susceptibilidade à neutropenia após exposição à clozapina pode ser transitória, de modo que o r isco hematológico da olanzapina decresceria à medida que o tempo decorrido após a suspensão da clozapina aumentasse. Sugerimos que pacientes que desenvolverem alterações hematológicas com clozapin...
متن کاملG-CSF plasma levels in clozapine-induced neutropenia.
BACKGROUND Clinical reports emphasize the therapeutic usefulness of granulocyte colony-stimulating factor (G-CSF) in clozapine-induced granulocytopenia. Only sparse information exists, however, on the natural course of endogenous G-CSF plasma levels in this condition. METHODS We monitored G-CSF and white blood cell (WBC) counts in a 73-year-old patient who developed granulocytopenia while bei...
متن کاملClozapine, agranulocytosis, and benign ethnic neutropenia.
C lozapine is an atypical antipsychotic that is effective in treatment resistant schizophrenia. The National Institute for Health and Clinical Excellence (NICE) guidelines for schizophrenia specify that ‘‘in individuals with evidence of treatment resistant schizophrenia, clozapine should be introduced at the earliest opportunity’’. A severe adverse effect of clozapine that limits its more wides...
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ژورنال
عنوان ژورنال: British Journal of Psychiatry
سال: 1994
ISSN: 0007-1250,1472-1465
DOI: 10.1192/bjp.164.6.850a